Antidiabetic Activities of an LC/MS Fingerprinted Aqueous Extract of Fagonia cretica L. in Preclinical Models
نویسندگان
چکیده
منابع مشابه
Erratum: Antidiabetic Activities of an LC/MS Fingerprinted Aqueous Extract of Fagonia cretica L. in Preclinical Models.
Diabetes mellitus is a chronic disease and one of the most important public health challenges facing mankind. Fagonia cretica is a medicinal plant used widely in the Punjab in Pakistan. A recent survey has demonstrated that traditional healers and herbalists frequently use this plant to treat diabetes. In the current study, the traditional medicine was prepared as a tea, and the profile of the ...
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According to traditional knowledge, Fagonia cretica has medicinal potential, especially against cancer and tumors. In the present study, this information was analyzed at laboratory level by performing cytotoxic, antitumor (potato disc) and DNA damage assay. Significant cytotoxic activity was found against brine shrimps at LD50 118.89 ppm, while antitumor assay showed that the extract inhibited ...
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BACKGROUND Plants have proved to be an important source of anti-cancer drugs. Here we have investigated the cytotoxic action of an aqueous extract of Fagonia cretica, used widely as a herbal tea-based treatment for breast cancer. METHODOLOGY/PRINCIPAL FINDINGS Using flow cytometric analysis of cells labeled with cyclin A, annexin V and propidium iodide, we describe a time and dose-dependent a...
متن کاملEffects of Fagonia cretica L. Constituents on Various Endocrinological Parameters in Rabbits
The effects of powdered Fagonia cretica plant and its two major triterpenoid saponins (saponin-I and saponin-II) on various blood endocrinological parameters. Prolactin namely, serum prolactin, serum thyrotropin, serum thyroxine and serum cortisol of normal male rabbits were investigated. Two major triterpenoid compounds, saponin-I and saponin-II, were isolated from its ethanolic extract by rep...
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ژورنال
عنوان ژورنال: Planta Medica
سال: 2017
ISSN: 0032-0943,1439-0221
DOI: 10.1055/s-0043-107616